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Aspirin-Exacerbated Respiratory Disease: How to Diagnose and Treat AERD with Desensitization

January 11 2026

Aspirin-Exacerbated Respiratory Disease: How to Diagnose and Treat AERD with Desensitization

AERD, or Samter's Triad, combines asthma, nasal polyps, and NSAID reactions. Diagnosis requires a supervised aspirin challenge. Desensitization with daily aspirin after surgery cuts polyp recurrence by 65% and restores smell in most patients.

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