Want something that works fast for erectile dysfunction? Avanafil, sold as Stendra, can start working in as little as 15–30 minutes for many men. It's one of the newer PDE5 inhibitors and is praised for quick onset and generally mild side effects.
Avanafil relaxes blood vessels in the penis so blood can flow in during sexual arousal. You need sexual stimulation for it to work—it won't cause an erection on its own. Typical doses are 50 mg, 100 mg, and 200 mg. Doctors often start you on 100 mg and adjust based on how you respond and side effects.
Take it 15–30 minutes before sex. Food doesn't stop it, but a very high-fat meal can slow how fast it kicks in. Expect effects to last about 4–6 hours, though this varies. Don’t take more than one dose in 24 hours.
Common side effects are headache, flushing, nasal congestion, and back pain. These are usually short lived. Serious but rare problems include sudden vision loss, sudden hearing loss, and priapism (an erection lasting more than 4 hours). If any of those happen, get emergency care right away.
Never take avanafil with nitrates (like nitroglycerin). That combo can cause a dangerous drop in blood pressure. Also be careful if you take alpha-blockers for prostate or blood pressure—your doctor may need to adjust doses. Strong CYP3A4 inhibitors (ritonavir, ketoconazole) raise avanafil levels and may mean you need a lower dose or a different drug.
Don't use avanafil if you have unstable heart disease, recent stroke or heart attack, or very low blood pressure. If you have diabetes, high blood pressure, or are on multiple medications, talk to your doctor first.
How does avanafil compare to others? It usually works faster than sildenafil (Viagra) and vardenafil, and it wears off sooner than tadalafil (Cialis). That makes it a good choice if you want quicker action without a long tail.
Want to try it? Get a prescription. Buying from a licensed pharmacy—local or reputable online—cuts the risk of counterfeit pills. Look for clear contact info, pharmacist availability, and verified review sites. Avoid stores that sell prescription drugs without asking for a prescription.
Bottom line: avanafil can be a solid, fast option for ED, but it’s not for everyone. Talk to a doctor, check interactions, start with a lower dose, and use trusted pharmacies. If side effects or heart concerns show up, seek medical advice right away.
